Harsh Bais, PhD

RESEARCH


 

Current Research

Single-molecule bioelectronics

Single-molecule bioelectronics
Over the past several decades, a variety of imaging techniques have enabled a wide range of studies of the structure, function, and dynamics of molecules at the single-molecule level. However, popular fluorescent single-molecule techniques generally cannot directly resolve temporal changes that occur on sub-millisecond timescales, as imaging times must accommodate the relatively slow rate of photon emission from single fluorophores.

   
CMOS electrochemical sensing

CMOS electrochemical sensing
We have demonstrated the ability to build large-scale arrays of potentiostats capable of highly parallel electrochemical "imaging." We are exploring new applications of this technology as a new mode for imaging biomolecular and biological systems.

   
CMOS-neural interfaces

CMOS-neural interfaces
Extracellular stimulation and recording of neural activity is an important tool in investigating the function of the nervous system.

   
Carbon-based electronics

Carbon-based electronics
Si CMOS is facing increasing challenges in continuing performance gains with channel length scaling due to the growing importance of fringe capacitance parasitics, short-channel effects due to degraded electrostatics, and gate leakage.

   
Integrated power electronics

Integrated power electronics
Delivering power to integrated circuits is becoming an increasingly complex challenge. On the high end, chips can demand in excess of 150 W of power at supply voltages of less than 1 V, leading to current demands approaching 200 A.

 

   
Piezoelectrics-on-CMOS

Piezoelectrics-on-CMOS
Traditional chemical and biological assays rely on secondary reporters for detection of binding events, as with the use of fluorescent reporters for microarrays or colorimetric enzyme labels for immunoassays.

   
Fluorescence lifetime imagers

Fluorescence lifetime imagers
Fluorescence lifetime based imaging systems have historically been limited by long acquisition times (on the order of seconds). Integration of FLIM systems onto CMOS provides the potential to increase acquisition speed an pave the way for new applications.